The Shikimate Pathway as an Entry to Aromatic Secondary Metabolism
نویسندگان
چکیده
منابع مشابه
The shikimate pathway as an entry to aromatic secondary metabolism.
The shikimate pathway is often referred to as the common aromatic biosynthetic pathway, even though nature does not synthesize a11 aromatic compounds by this route. This metabolic sequence converts the primary metabolites PEP and erythrose-4-P to chorismate, the last common precursor for the three aromatic amino acids Phe, Tyr, and Trp and for p-amino and p-hydroxy benzoate (Fig. 1). The shikim...
متن کاملShikimate Pathway and Aromatic Amino Acid Biosynthesis
The shikimate pathway consists of seven enzymatic reactions whose end product chorismate is the precursor for the synthesis of the aromatic amino acids Phe, Tyr and Trp. In fungi and plants, chorismate is a precursor for many specialised metabolites (i.e. secondary metabolites) that play an important role in the plant’s interaction with its environment. The shikimate pathway and aromatic amino ...
متن کاملThe Shikimate Pathway: Aromatic Amino Acids and Phenylpropanoids
Shikimic acid and its role in the formation of aromatic amino acids, benzoic acids, and cinnamic acids is described, along with further modifications leading to lignans and lignin, phenylpropenes, and coumarins. Combinations of the shikimate pathway and the acetate pathway are responsible for the biosynthesis of styrylpyrones, flavonoids and stilbenes, flavonolignans, and isoflavonoids. Terpeno...
متن کاملThe Shikimate Pathway: Early Steps in the Biosynthesis of Aromatic Compounds.
The shikimate pathway was discovered as the biosynthetic route to the aromatic amino acids phenylalanine, tyrosine, and tryptophan through the classic studies of Bernhard Davis and David Sprinson and their collaborators. This pathway has been found only in microorganisms and plants. Phenylalanine and tryptophan are essential components of animal diets, and animals synthesize tyrosine in a singl...
متن کاملThe metabolism of shikimate in the rat.
In the rat, shikimate was metabolized and excreted as hippurate, hexahydrohippurate, 3,4,5,6-tetrahydrohippurate, t-3,t-4-dihydroxycyclohexane-r-1-carboxylate and c-3,t-4-dihydroxycyclophexane-r-1-carboxylate, conjugates of catechol and CO2. The metabolism was entirely dependent on various initial microbial transformations in the gut, metabolite formation being suppressed in animals pretreated ...
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ژورنال
عنوان ژورنال: Plant Physiology
سال: 1995
ISSN: 0032-0889,1532-2548
DOI: 10.1104/pp.107.1.7